

International Training Provider

Pain Relief
Inhaled Analgesia: Entonox
Entonox, commonly referred to as gas and air, consists of a stabilised mixture of 50% nitrous oxide and 50% oxygen. It is the most frequently used medical pain relief in many clinical settings because of its ease of administration and rapid clearance from the system. The birthing person inhales the gas through a mouthpiece or a mask during a contraction.
Administration and Timing
Instruction for Entonox focuses on timing. Because the gas takes approximately 15 to 20 seconds to reach peak effectiveness in the bloodstream, the person must begin inhaling as soon as they feel a contraction starting. Waiting until the contraction is at its peak results in the sedative effect arriving after the pain has already begun to subside. Deep, steady breaths are more effective than short, shallow gasps.
Effects on the Birthing Person
Entonox does not eliminate pain; instead, it alters the perception of pain, making it feel more manageable or distant. Many users report a lightheaded or "floaty" sensation. Common side effects include nausea, vomiting, or a dry mouth. Because the user controls the intake, they can stop at any time, and the effects usually dissipate within a few minutes of breathing normal room air.
Effects on the Baby
There are no known long-term side effects on the baby. The nitrous oxide enters the baby’s circulation via the placenta but is cleared quickly through the baby’s own respiration after birth. It does not interfere with the baby's alertness or the initiation of breastfeeding.
Systemic Opioids: Pethidine and Diamorphine
Opioids are strong analgesics administered via intramuscular injection, usually into the buttock or thigh. In some hospital settings,
Patient-Controlled Analgesia (PCA) allows the birthing person to self-administer small doses of remifentanil through an intravenous line. Pethidine and diamorphine are the most traditional choices in standard maternity wards.
Mechanism of Action
These drugs work by blocking pain signals in the brain and spinal cord. They are particularly useful during the late latent phase or early active phase of labour when a person is becoming exhausted and needs rest. They provide a sedative effect, often allowing the person to sleep between contractions.
Maternal Side Effects
Opioids can cause significant drowsiness, which some people find distressing if they wish to remain alert. Nausea is a very common side effect, often requiring an additional anti-emetic injection. These drugs can also slow down gastric emptying, which is a consideration if further interventions like general anaesthesia become necessary.
Impact on the Baby
Opioids cross the placenta easily. If administered too close to the time of delivery (usually within two to four hours), the baby may be born with respiratory depression. This means the baby might be slow to take their first breath or appear very sleepy, which can hinder the first feed. In cases of respiratory depression, medical staff may administer Naloxone to the baby to reverse the effects of the opioid.
Regional Anaesthesia: The Epidural
An epidural is the most complex and effective form of pain relief available. it involves the injection of local anaesthetics and often an opioid into the epidural space, which surrounds the spinal cord. This blocks the transmission of pain signals from the spinal nerves to the brain, usually resulting in a total or near-total loss of sensation from the waist down.
The Procedure
The administration of an epidural requires a specialist anaesthetist. The birthing person must sit very still, often hunched over, or lie on their side in a curled position. A needle is inserted between the vertebrae of the lower back to place a fine plastic catheter. The needle is then removed, and the catheter is taped in place to allow for continuous or bolus delivery of the medication.
Clinical Requirements and Monitoring
Because an epidural can cause a sudden drop in maternal blood pressure, an intravenous (IV) drip is required to maintain fluid volume. Continuous electronic fetal monitoring (EFM) is also mandatory to ensure the baby is responding well to the physiological changes in the parent. Movement is usually restricted; while "mobile epidurals" exist, most people find their legs feel heavy or numb, requiring them to stay in bed.
Maternal Effects and Risks
The primary benefit is the complete relief of pain while remaining fully conscious. However, the lack of sensation often means the birthing person cannot feel their bladder, necessitating a urinary catheter. There is an increased likelihood of a prolonged second stage of labour because the urge to push is diminished. This often leads to a higher rate of instrumental deliveries (forceps or ventouse). A rare but significant side effect is a "spinal headache," caused by a puncture of the dural sac, which requires a specific follow-up procedure called a blood patch.
Effects on the Baby
The drugs used in an epidural enter the maternal bloodstream in small amounts, but the direct effect on the baby is usually minimal compared to systemic opioids. The primary risk to the baby is secondary to maternal hypotension (low blood pressure), which can reduce oxygen flow to the placenta. This is why continuous heart rate monitoring is used to identify any distress early.
Combined Spinal-Epidural (CSE)
A CSE is often used when rapid pain relief is needed, such as in a very intense labour or during preparation for an emergency caesarean. It involves an initial injection of medication directly into the spinal fluid (the spinal), followed by the placement of an epidural catheter for ongoing relief.
Immediate Action The spinal component works almost instantly, providing a dense block of sensation. This is useful for surgical procedures. The epidural component provides the longevity needed if the labour is expected to continue for several more hours. The risks and monitoring requirements are identical to those of a standard epidural.
Local Anaesthetics: Pudendal Block and Infiltration
Local anaesthetics are used specifically for the perineal area, rather than providing systemic pain relief for contractions. These are most common during the second and third stages of labour.
Perineal Infiltration
If an episiotomy (a surgical cut to the perineum) is required, or if a tear needs suturing after birth, a local anaesthetic is injected directly into the perineal tissue. This numbs the immediate area quickly. It has no effect on the baby or the progress of labour.
Pudendal Block
A pudendal block involves injecting local anaesthetic through the vaginal wall to numb the pudendal nerve. This is typically used just before an instrumental birth (forceps or ventouse). It provides effective relief for the lower vagina and perineum but does not numb the uterus or stop the sensation of contractions.
Comparative Summary for Educators
When teaching these options, use a balanced approach. Parents should understand that pain relief is not a "failure" of the physiological process but a tool available to them.
Key Comparison Points:
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Entonox: High control, low duration, no effect on labour progress.
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Opioids:Moderate relief, sedative, potential for neonatal sleepiness.
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Epidural:High relief, low mobility, requires IV/monitoring, may increase intervention rates.
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Local: Specific to the birth outlet, used for interventions or repairs.
Encourage parents to consider their "pain relief ladder." Most clinical guidelines suggest starting with the least invasive methods (non-medical) and moving toward medical interventions only as needed.
However, in cases of induction of labour where contractions can be more intense and sudden, parents may choose to access an epidural earlier in the process.
Informed Consent and Decision Making
The educator must stress the importance of the B-R-A-I-N acronym when discussing these options in a clinical setting. This helps parents ask the right questions in the heat of the moment:
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B-enefits: How will this help me right now?
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R-isks: What are the side effects for me and the baby?
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A-lternatives: Is there something else I can try first?
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I-ntuition: What does my gut tell me?
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N-othing: What happens if we wait 30 minutes before deciding?
By providing this framework, you move beyond just listing drugs and instead give parents the skills to navigate their care dynamically.
Ensure they understand that hospital policies may vary; for instance, some units may not offer remifentanil PCA, or the availability of an anaesthetist for an epidural might be delayed during busy periods. Knowing these realities helps parents manage expectations.